Table 1.

The effects of formaldehyde on the histopathological characteristics during lung fibrosis. Groups of mice were submitted to bleomycin injection (1.5 U/kg, orotracheal route) and after 7 days were exposed to FA inhalation (0.75 ppm, 1 h/day, 15 days). Non-manipulated animals were used to basal parameters. After 24 h of last exposure to FA or 14 days after fibrosis development, the lung mucus, oedema and interstitial tickening were evaluated. Data represent the mean ± SEM of 6 animals. *P < 0.05 compared to the B group.

Groups	Mucus	Oedema	Interstitial tickening
B	0,33	0,16	0,16
FA	1,33*	1,33*	1,50*
F	2,50*	2,25*	2,75*
F + FA	2,20*	2,60*	2,00*