Figure 1.

SMGA mRNA presence and androgen responsiveness within LNCaP cells. (A) Representative autoradiograms from Northern analyses using RNA isolated from LNCaP cells treated with either vehicle (lane 1) or increasing amounts of androgen (R1881; 0.1–10 nM) with ³²P-labeled DNA probes representing human SMGA, SRF, or murine Nkx 3.1 are shown. (B) Striped bars represent each specific band appearing in (A) derived from cells cultured in the presence of vehicle, while the black bars represent those bands appearing in (A) in the presence of 10 nM R1881. The results are shown as the mean ± SE. *Statistical significance in the presence of R1881 versus its absence at p < 0.05.