Figure 2.

Representation of conserved regions of the small GTPases. The regions corresponding to the two consensus sequences used are shown in (A, RAB subfamily) and (B, ARF/Sar1 subfamily). The upper lanes in each figure show the two consensus sequences of the subfamilies. The lower lanes show the alignment of the novel small GTPases of the two subfamilies. The highly conserved residues of the proteins are indicated in black-shaded boxes and similar residues are in gray-shaded boxes. (C) Schematic shows the conserved domains in the nine small GTPases.