. Author manuscript; available in PMC: 2018 May 31.

Published in final edited form as: Endocrinol Metab Clin North Am. 2017 Sep 29;46(4):983–1007. doi: 10.1016/j.ecl.2017.07.008

Table 1.

Drugs available for the treatment of secondary hyperparathyroidism in CKD/ESRD

Drug	Brand Name	Available in US	Oral or IV	Starting doses	Effect on calcium^*	Effect on phosphorous^*
Calcitriol	Rocaltrol/Calcijex	Yes	Both	1–2 μg IV thrice weekly	NA	NA
Paricalcitol	Zemplar	Yes	Both	2–4 μg IV thrice weekly	Less hypercalcemia	Less hyperphosphatemia
Alfacalcidol	One-Alpha (Canada)	No	Both		Similar to calcitriol	Similar to calcitriol
Doxercalciferol	Hectorol	Yes	Both	2–4 μg IV thrice weekly	Similar to calcitriol	Similar to calcitriol
Maxacalcitol	Oxarol (Japan)	No	IV		Similar to calcitriol	Similar to calcitriol
Falecalcitriol	Hornel (Japan)	No	Oral		Similar to calcitriol	Similar to calcitriol

compared to calcitriol