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. Author manuscript; available in PMC: 2018 Jun 7.
Published in final edited form as: J Am Chem Soc. 2017 May 24;139(22):7533–7539. doi: 10.1021/jacs.7b01599

Figure 2.

Figure 2

Telomere RNA G-quadruplex binding selectivity of hnRNPA1. The experiment was performed with hnRNPA1 and 32P-labeled 6-mer UUAGGG RNA (tetramer), 12-mer UUAGGGUUAGGG RNA (dimer), 18-mer UUAGGGUUAGGGUUAGGG RNA (dimer), 24-mer UUAGGGUUAGGGUUAGGGUUAGGG RNA (intramolecular G-quadruplex), and single-stranded GAGUAACCCGUAUCGUGA RNA using 8% PAGE in 1× TBE buffer with 20 mM NaCl at 4 °C for 2 h (80 V).