Skip to main content
. 2017 Apr 4;74(15):2795–2813. doi: 10.1007/s00018-017-2502-4

Fig. 4.

Fig. 4

Interaction of CypD with mitochondrial proteins. CypD can modulate the PTP opening through interaction with proteins in the matrix and IMM. Interaction of CypD with “PTP inducers” (red background) sensitizes PTP opening and induces cell death whereas the interaction with “PTP blockers” (blue background) inhibits pore opening and prevents cell death