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. 2018 Mar 9;5:448–456. doi: 10.1016/j.toxrep.2018.02.019

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© 2018 Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Photomicrograph showing sections of rat liver of Control (0.0 mg/kg BW/day) a: Hepatocytes (H), Portal Vein (PV), Blood sinusoids (BS), Hepatic Artery (HA), Bile Duct (BD), interlobular Connective Tissue; rats exposed to High dose (32.33 mg/kg BW/day) b: Damaged Bile Duct (BD), Ruptured Portal Vein (PV), dilated blood sinusoids (BS), Damaged Hepatic Artery (HA), Hypertrophy of Hepatocytes (H), Disrupted Connective Tissue (CT), Focal Necrosis (F); rats exposed to medium dose (12.12 mg/kg BW/day) c: Mild Dilation of Blood Sinusoids (BS), Partial clogging of Bile Duct (BD) and Portal Vein (PV), Damaged Hepatic Artery (HA) and Connective Tissue (CT), Hypertrophy of Hepatocytes (H), Stagnation of Bile (B), mild Vacuolation (V), Focal Necrosis (F); rats exposed to with low dose (6.46 mg/kg BW/day) d: Hypertrophy of Hepatocytes (H), Clogged Portal Vein (PV), (H and E staining, 200 X).