Table 2.
Histopathological changes in liver of male Wistar rats following oral exposure to different doses of FPN.
| Findings | Groups |
|||
|---|---|---|---|---|
| Control | Exposed |
|||
| High | Medium | Low | ||
| Vacuolation (V) | ND | * * | * * | * |
| Dilated sinusoid (DS) | ND | * * | * * | ND |
| Hypertrophy of hepatocytes (H) | ND | * * * | * * | * |
| Stagnation of bile (B) | ND | * | ** | ND |
| Damaged hepatic artery (HA) | ND | * | * * | ND |
| Degeneration/Clogging of bile duct (BD) | ND | * * * * | * * * | ND |
| Focal necrosis (F) | ND | * | ND | ND |
| Degenerated/Thrombosis/Clogged portal vein (PV) | ND | ND | ND | * * * * |
Histopathological findings in the liver of male Wistar albino rats with different groups indicated, (ND) as Not detected, (*) as low, (* *) as medium, (* * *) as high and (* * * *) as severe levels of histoarchitectural damage.