Table 2.
Correlations Between CGPs and Related Gene Mutations
| Gene Mutation | No. of Cases | Predominant Pattern, No. (%) | χ2 | P Value | |
|---|---|---|---|---|---|
| Patterns With CGPs | Patterns Without CGPs | ||||
| EGFR | |||||
| No | 120 | 54 (45.0) | 66 (55.0) | 0.102 | .749 |
| Yes | 236 | 102 (43.2) | 134 (56.8) | ||
| ALK | |||||
| No | 332 | 139 (41.9) | 193 (58.1) | 7.628 | .006 |
| Yes | 24 | 17 (70.8) | 7 (29.2) | ||
| KRAS | |||||
| No | 335 | 146 (43.6) | 189 (56.4) | 0.131 | .718 |
| Yes | 21 | 10 (47.6) | 11 (52.4) | ||
| AKT1 | |||||
| No | 355 | 155 (43.7) | 200 (56.3) | 1.286 | .257 |
| Yes | 1 | 1 (100) | 0 (0) | ||
| HER2 | |||||
| No | 351 | 156 (44.4) | 195 (55.6) | 3.956 | .047 |
| Yes | 5 | 0 (0) | 5 (100) | ||
| BRAF | |||||
| No | 355 | 155 (43.7) | 200 (56.3) | 1.286 | .257 |
| Yes | 1 | 1 (100) | 0 (0) | ||
| ROS1 | |||||
| No | 355 | 156 (43.9) | 199 (56.1) | 0.782 | .376 |
| Yes | 1 | 0 (0) | 1 (100) | ||
| P110 | |||||
| No | 346 | 150 (43.4) | 196 (56.6) | 0.531 | .466 |
| Yes | 9 | 5 (55.6) | 4 (44.4) | ||
CGP, complex glandular pattern.