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(a) SEM images of S. aureus biofilm coupon using SBPHMB/Instillation only for 24-h identifies dense coccoid bacteria embedded in EPS after treatment; (b) demonstrates an overall reduction in S. aureus biofilm after 24-h treatment with NPWTi using SBPHMB; (c) illustrates P. aeruginosa biofilm coupon using SPHMB/Instillation only for 24-h; (d) after 24-h treatment with NPWTi using SBPHMB. Arrows indicate biofilm aggregates.
