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. 2018 Apr 27;9(32):22559–22570. doi: 10.18632/oncotarget.25176

Figure 2.

Figure 2

(A) Frequency of mutations (N = 518) in never smokers with lung cancer. *21 tumor samples of patients were tested only for EGFR; 69 tumor samples were tested only for EGFR and ALK (1 out of 69 was tested also for ROS-1); 43 patients’ tumor samples were tested using multigene Next Generation Sequencing (NGS) assays: Sequenom MassARRAY (N = 22) and MiSeq Illumina (N = 21); 15 out of 43 available patients’ tumor samples with no detected mutations when tested with NGS assays were tested for ROS-1. (B) Frequency of mutations based on ethnicity. There are more Asian having EGFR: of the 236 Asian 155 had EGFR (66%); of the rest (n = 279), 141 had EGFR (51%) (Fisher exact p = 0.00066).