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| Cell line | MGMT promoter | LGK974 [μM] | TMZ [μM] | γ-irradiation [Gy] |
|---|---|---|---|---|
| GBM1 | methylated | 1 | 5 | 2 |
| JHH520 | methylated | 3 | 10 | 6 |
| GBM10 | unmethylated | 6 | 70 | 2 |
| SF188 | unmethylated | 1 | 40 | 2 |
Each cell line was treated with different dosages of TMZ and LGK974. Cell viability was taken as readout.
