Table 2. Ongoing trials of CART cells in glioblastoma.
| NCT number | Tumour type | Target | Mode of delivery |
|---|---|---|---|
| NCT02331693 | Advanced Glioma | EGFR | Systemic infusion (IV) |
| NCT02209376 | Glioblastoma Multiforme | EGFRvIII | Systemic infusion (IV) |
| NCT02844062 | Glioblastoma Multiforme | EGFRvIII | Systemic infusion (IV) |
| NCT01454596 | Glioblastoma Multiforme | EGFRvIII | Systemic infusion with aldesleukin (IL-2) (IV) |
| NCT02937844 | Glioblastoma Multiforme | PD-L1 | Systemic infusion (three-day split) (IV) |
| NCT02575261 | Glioma | EphA2 | Systemic infusion (IV) |
| NCT02664363 | Glioblastoma Multiforme | EGFRvIII | Systemic infusion (IV) Companion imaging study. |
| NCT01082926 | Brain tumours | IL13Rα2 | Intratumoral |
| NCT02208362 | High grade glioma | IL13Rα2 | Intratumoral |
| NCT02442297 | Glioblastoma Multiforme | Her2 | Intratumoral |
| NCT01109095 | Glioblastoma Multiforme | Her2 (CMV specific T cells) | Systemic infusion (IV) |