Figure 1. Treatment of TNBC PDX explants recapitulates results observed in TNBC cell lines.
Ex vivo treatments of TU-BcX-2O0 with LBH589 at 100nM for 72 hours. All data was obtained using qRT-PCR and normalized to actin and DMSO. Error bars represent SEM and significantly different *p < 0.05, ***p < 0.001. TU-BcX-2O0 and TU-BcX-4IC was analyzed in duplicate, TU-BcX- 2K1 and MDA-MB-231 were analyzed in triplicate.