Skip to main content
. 2018 Apr 9;37(10):e96553. doi: 10.15252/embj.201796553

Figure EV3. Salicylate treatment reduces inflammation and improves growth in Opa1 KO mice.

Figure EV3

  • A
    Expression of NF‐κB target genes in muscles of loxP and KO mice treated with sodium salicylate (Sal) or with PBS (PBS).
  • B, C
    Circulating IL‐6 (B) and IL‐1β (C) measured in plasma of loxP and KO mice treated or not with sodium salicylate.
  • D
    Body weight increase in loxP and KO mice treated or not with salicylate for 20 days.
  • E
    Distribution of myofiber size in quadriceps muscles from loxP and KO mice treated or not with salicylate.
  • F, G
    Igf1 (F) and Fos (G) mRNA levels in liver from salicylate‐treated and non‐treated mice.
Data information: Data represent mean ± SEM. *P < 0.05 vs. control loxP mice. # P < 0.05 vs. KO mice. Data were obtained from 8‐ to 10‐week‐old loxP and KO mice (n = 6). Data were analyzed using analysis of variance with Tukey's post hoc test.