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Advantages and disadvantages of new drugs for P. aeruginosa infections.
| Advantages |
| High activity against P. aeruginosa including MDR strains |
|
|
| Predictable PK |
|
|
| Good safety profile and tolerability |
|
|
| Carbapenem sparing |
|
|
| Rapid tissue distribution |
|
|
| Disadvantages |
|
|
| Increased costs |
|
|
| No oral formulations to allow step-down therapy |
|
|
| Superinfection with even more resistant bacteria or fungi |
