Table 3. Overview of the antimicrobial activity of 696 Cap18 derivatives.
MIC [μg/ml] | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
>32 | 32 | 16 | 8 | 4 | 2 | 1–2 | 1 | 0.5–1 | 0.5 | ||
A. salmonicida ATCC33658 | |||||||||||
Number of variants | 3 | 9 | 13 | 40 | 186 | 388 | 23 | 30 | 3 | 1 | |
% | 0.4% | 1.3% | 1.9% | 5.7% | 26.7% | 55.7% | 3.3% | 4.3% | 0.4% | 0.1% | |
Y. ruckeri 392/2003 | |||||||||||
Number of variants | 10 | 13 | 24 | 52 | 127 | 375 | 26 | 62 | 6 | 1 | |
% | 1.4% | 1.9% | 3.4% | 7.5% | 18.2% | 53.9% | 3.7% | 8.9% | 0.9% | 0.1% | |
S. Typhimurium LT2 | |||||||||||
Number of variants | 5 | 9 | 11 | 63 | 342 | 234 | 27 | 5 | 0 | 0 | |
% | 0.7% | 1.3% | 1.6% | 9.1% | 49.1% | 33.6% | 3.9% | 0.7% | 0% | 0% | |
L. lactis IL1403 | |||||||||||
Number of variants | 36 | 11 | 42 | 177 | 269 | 145 | - | 14 | - | 2 | |
% | 5.2% | 1.6% | 6.0% | 25.4% | 38.7% | 20.8% | - | 2% | - | 0.3% |
Cap18 variants with unchanged MIC value compared to the original Cap18 are highlighted in grey