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. 2018 May 31;13(5):e0197742. doi: 10.1371/journal.pone.0197742

Table 3. Overview of the antimicrobial activity of 696 Cap18 derivatives.

MIC [μg/ml]
>32 32 16 8 4 2 1–2 1 0.5–1 0.5
A. salmonicida ATCC33658
Number of variants 3 9 13 40 186 388 23 30 3 1
% 0.4% 1.3% 1.9% 5.7% 26.7% 55.7% 3.3% 4.3% 0.4% 0.1%
Y. ruckeri 392/2003
Number of variants 10 13 24 52 127 375 26 62 6 1
% 1.4% 1.9% 3.4% 7.5% 18.2% 53.9% 3.7% 8.9% 0.9% 0.1%
S. Typhimurium LT2
Number of variants 5 9 11 63 342 234 27 5 0 0
% 0.7% 1.3% 1.6% 9.1% 49.1% 33.6% 3.9% 0.7% 0% 0%
L. lactis IL1403
Number of variants 36 11 42 177 269 145 - 14 - 2
% 5.2% 1.6% 6.0% 25.4% 38.7% 20.8% - 2% - 0.3%

Cap18 variants with unchanged MIC value compared to the original Cap18 are highlighted in grey