Table 2.
Comparison of PET parameters between responders and non-responders (n = 35)
| FMI parameters | Responders (%) | Non-responders (%) | p value | ROC (AUC) |
|---|---|---|---|---|
| Combined (PT + LNs) | ||||
| TLG40% (g) | ||||
| Baseline | 112.4 ± 98.2 | 264.7 ± 361.0% | 0.192 | – |
| Δ post-wk 1 | −56.3 ± 31.0 | −18.0 ± 38.8 | 0.007* | 0.825 |
| Δ post-wk 2 | −68.7 ± 20.9 | −48.8 ± 33.3 | 0.131 | – |
| SUVmax | ||||
| Baseline | 14.2 ± 5.2 | 16.6 ± 5.9 | 0.269 | – |
| Δ post-wk 1 | −27.8 ± 21.1 | −8.1 ± 18.8 | 0.034* | 0.764 |
| Δ post-wk 2 | −32.5 ± 23.0 | −21.4 ± 19.8 | 0.158 | – |
| Primary tumor (PT) | ||||
| TLG40% (g) | ||||
| Baseline | 87.8 ± 80.1 | 233.5 ± 291.2 | 0.104 | – |
| Δ post-wk 1 | −41.3 ± 23.5 | −18.3 ± 37.7 | 0.069 | – |
| Δ post-wk 2 | −60.2 ± 17.1 | −48.2 ± 34.9 | 0.310 | – |
| SUVmax | ||||
| Baseline | 14.7 ± 4.7 | 16.4 ± 6.1 | 0.498 | – |
| Δ post-wk 1 | −20.6 ± 12.7 | −4.9 ± 18.5 | 0.050 | – |
| Δ post-wk 2 | −27.7 ± 14.7 | −20.5 ± 18.0 | 0.224 | – |
| Lymph nodes (LNs) | ||||
| TLG40% (g) | ||||
| Baseline | 50.6 ± 57.8 | 70.9 ± 88.4 | 0.532 | – |
| Δ post-wk 1 | −56.5 ± 39.5 | −16.6 ± 50.9 | 0.085 | – |
| Δ post-wk 2 | −65.6 ± 28.2 | −52.9 ± 45.6 | 0.790 | – |
| SUVmax | ||||
| Baseline | 10.9 ± 5.1 | 11.8 ± 5.2 | 0.859 | – |
| Δ post-wk 1 | −32.1 ± 24.1 | −18.8 ± 16.6 | 0.391 | – |
| Δ post-wk 2 | −34.8 ± 28.1 | −34.9 ± 12.2 | 0.533 | – |
*Statistically significant difference