Table 3.

Mandatory procedures to be performed before strontium-89, samarium-153, phosphorus-32 or radium-223 administration

Procedure	Objective	Timing
Medical history	To obtain patient demographics, indication for therapy, concomitant medications	Qualification for treatment on day of treatment
Life expectancy estimation	To confirm at least 4–6 weeks (preferably 3 months)	Qualification for treatment
Bone scan	To evaluate extent of disease	No longer than 4–8 weeks prior to therapy
Radiological imaging	To exclude severe lytic lesions with risk of pathological bone fracture or cord compression	As required
Complete blood count, d-dimer, serum creatinine	To exclude haematological, biochemical contraindication to therapy	No longer than 1–2 weeks prior to therapy; If required repeat on day of treatment
Pregnancy test		On day of treatment