Table 1.

Clinical and molecular variables of the EORTC 22033 dataset and the external glioma datasets (WHO grade II and III) used for this study

Variable	Modality	EORTC 22033	TCGA-1	TCGA-2	AGlioma	p value
N		132	201	197	227	–
Sexa	M	74	114	111	72	0.6234
	F	58	87	86	42
Age (year)b	Median	43	41	40	42	0.3683
	Min	20	17	14	23
	Max	71	87	75	74
Gradea	II	132	95	96	0	< 0.0001
	III	0	106	101	227
Subtypea,c	IDHwt	12	37	36	50	0.0105
	IDHmt non-codel	80	108	107	97
	IDHmt codel	40	56	54	80

^a Chi-squared test

^b Kruskal and Wallis test

^c IDH status inferred from G-CIMP status; see Methods