Table 1.
Clinopathological characteristics of the 44 patients with AIS of the cervix who were treated with LEEP
| Parameters | Number of patients | Percent (%) |
|---|---|---|
| Age at diagnosis, (Mean;range) | 36.1 ± 14.2 (28–55) | |
| Baseline parity | ||
| Nulliparous | 14 | 31.8 |
| Pluriparous | 30 | 68.2 |
| Presentation | ||
| Contact bleeding | 2 | 4.5 |
| Vaginal discharge | 1 | 2.3 |
| Asymptomatic | 41 | 93.2 |
| Referral Cytology | ||
| ASCUS | 13 | 29.5 |
| AGC | 4 | 9.1 |
| LSIL | 8 | 18.2 |
| HSIL | 13 | 29.5 |
| AIS | 1 | 2.3 |
| NILM | 5 | 11.4 |
| High-risk HPV | ||
| Negative | 4 | 9.1 |
| Positive | 39 | 88.6 |
| Unkonwn | 1 | 2.3 |
| Height of LEEP specimens(cm; range) | 1.1 ± 0.2 (0.7–2) | |
| Depth of LEEP specimens(cm; range) | 1.5 ± 0.3 (1–2) | |
| Status of LEEP margin | ||
| Negative | 33 | 70.5 |
| Positive | 10 | 29.5 |
| Not evaluable | 1 | 2.3 |
| AIS detected by | ||
| Papanicolaou test | 1 | 2.3 |
| Punch biopsy | 12 | 27.3 |
| LEEP only | 31 | 70.5 |
| Multifocality | ||
| Yes | 4 | 9.1 |
| No | 40 | 90.9 |
| Coexisting squamous disease | ||
| CIN I | 5 | 11.4 |
| CIN II | 8 | 18.2 |
| CIN III | 25 | 54.5 |
| Absent | 6 | 13.6 |
| Follow-up (month;range) | 36.9 ± 18.7 (3–101) | |
| Status at the last contact | ||
| Abnormal cytology | 1 | 2.3 |
| Positive high-risk HPV | 6 | 13.6 |
| Both positive | 1 | 2.3 |
| Both negative | 36 | 81.8 |
Note:AIS adenocarcinoma in situ, LEEP loop electrosurgical excisional procedure, ASCUS atypicai squamous cells, AGC,atypical glandular cell, HSIL high-grade squamous intraepithelial lesions, NILM negative for intraepithelial lesion or malignancy, CIN cervical intraepithelial lesion