Table 4.
Quality assessment of included case series and case reports
| Study: First Author Place of study (Year) |
Score for studiesa | Total score | ||||||
|---|---|---|---|---|---|---|---|---|
| What is the overall degree of presentation of study details? | Detailed presentation of study participant characteristics? | Case definition clearly reported? | Clear description of malaria treatment reported? | Clear reporting on the follow-up period? | Appropriate reporting of efficacy outcomes? | Appropriate reporting of safety outcomes? | ||
| Case series | ||||||||
| Mayer Russia (1919) [62] |
2 | 0 | 2 | 2 | 2 | 2 | 2 | 12 |
| Panse Africa (1902) [63] |
2 | 0 | 2 | 2 | 1 | 1 | 0 | 8 |
| Glogner Indonesia (1901) [64] | 2 | 2 | 2 | 2 | 1 | 1 | 0 | 10 |
| Ollwig Africa (1899) [65] |
2 | 1 | 1 | 2 | 1 | 2 | 2 | 11 |
| Cardamatis Greece (1898) [66] |
1 | 0 | 1 | 2 | 1 | 1 | 1 | 7 |
| Röttger Germany (1895) [67] |
2 | 2 | 1 | 2 | 1 | 2 | 2 | 12 |
| Ferreira Brazil (1893) [68] |
2 | 2 | 1 | 2 | 2 | 2 | 2 | 13 |
| Parenski and Blatteis Europe (1893) [69] |
1 | 0 | 1 | 2 | 1 | 1 | 1 | 7 |
| Thayer USA (1892) [70] |
2 | 2 | 1 | 2 | 1 | 2 | 2 | 12 |
| Guttmann and Ehrlich Germany (1891) [29] |
2 | 2 | 2 | 2 | 1 | 2 | 2 | 13 |
| Case reports | ||||||||
| Mühlens Germany (1921) [71] | 1 | 0 | 2 | 2 | 2 | 2 | 0 | 9 |
| Atkinson China (1903) [72] |
1 | 1 | 1 | 2 | 2 | 2 | 1 | 10 |
| Sivers Germany (1901) cited by Merck (1922) [73, 74] |
1 | 2 | 2 | 2 | 1 | 1 | 2 | 11 |
| Anonymous Germany (1893) [75] |
2 | 2 | 2 | 2 | 2 | 2 | 2 | 14 |
| Trintignan India (1882) cited by Röttger (1895) [67] |
1 | 1 | 1 | 2 | 2 | 2 | 0 | 9 |
aThe items are scored 0 (not reported), 1 (reported but inadequate) or 2 (reported and adequate). The global ideal score was 14 for case series and case reports