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. 2018 May 31;13(5):e0197448. doi: 10.1371/journal.pone.0197448

Fig 2. Predicted natural rubber degradation pathway of Steroidobacter cummioxidans strain 35Y.

Fig 2

The pathway comprises of five steps: (1) biosynthesis of rubber oxygenases and extracellular oxidative cleavage of polyisoprene chains, (2) import of oligoisoprenes, (3) β-oxidation, (4) acetyl-CoA and propionyl-CoA metabolism, and (5) anaplerotic reactions and gluconeogenesis. RoxA: Rubber oxygenase A, RoxB: Rubber oxygenase B, ODTD: 12-oxo-4,8-dimethyltrideca-4,8-diene-1-al, Mce: Mammalian cell entry protein, Mla: An ABC transport system that maintains lipid asymmetry, TBDRs: TonB-dependent outer membrane receptors, FACS: fatty acyl coenzyme A (CoA) synthetase: FadL: It encodes outer membrane proteins/ transporters involved in long-chain fatty acid, TCA: Tricarboxylic acid cycle, PEP: Phosphoenolpyruvate.