Sundew-inspired hydrogel encapsulating rhMG53 reduces skin scar formation. (A) Excisional wounds of mice were treated with saline, rhMG53, Sundew-inspired hydrogel, or Sundew-inspired hydrogel encapsulating rhMG53. Representative macroscopic H&E (top panels) and Masson’s trichrome staining (bottom panels) images of the skin were taken at day 30 after injury. Images show decreased skin scar formation (collagen deposition, staining in blue). (B) Quantification of skin thickness in wound site on day 30 following excisional wounding from the mice treated with saline, rhMG53, Sundew-inspired hydrogel, or Sundew-inspired hydrogel encapsulating rhMG53 (mean ± SD; **P < 0.01, n = 4 per group).