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. 2018 Apr 12;19(4):1177. doi: 10.3390/ijms19041177

Figure 2.

Figure 2

Crystal structures of a human EAAT1: (a) Topology diagram for SLC1 family transporters. The trimerization domain is in light blue; the transport domain is in light green; helical hairpin1 (HP1) is in green; HP2 is in cyan; and TM4 is in yellow and red; (b) A ribbon diagram of a human EAAT1 colored as in (a), with L-aspartate (spheres) and a sodium ion (yellow). PDBID:5LLU; (c) Ribbon (left) and surface (right) diagram of a human EAAT1 trimer viewed from extracellular face. Protomers of the trimer are colored in pink, light blue and light green; (d) Ribbon diagram of a human EAAT1 with the trimerization domain in light blue, and the transport domain in light green; (e) Ribbon diagram of a human EAAT1 with d,l-threo-b-benzyloxyaspartate (TBOA) (spheres) as shown in (b). Notice that the tip of HP2 (cyan) is open and does not cover TBOA. PDBID:5MJU. Pictures are generated using QtMG [40].