Table 7.
miRNA/mRNA pairs matched on the basis of mRNA and miRNA profiling results.
| Cell Treatments | miRNA | Fold Change | mRNA Target | Gene Name |
|---|---|---|---|---|
| EVE 5 nM | miR-8485 | 9.183 | CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| miR-5194 | 2.732 | ARPC3 | actin related protein 2/3 complex, subunit 3, 21 kDa | |
| EVE 100 nM | miR-8485 | 5.372 | CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| KAL1 | Kallmann syndrome 1 sequence | |||
| UBL3 | ubiquitin-like 3 | |||
| IRS2 | insulin receptor substrate 2 | |||
| CTGF | connective tissue growth factor | |||
| LBH | limb bud and heart development | |||
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | |||
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | |||
| CYBRD1 | cytochrome b reductase 1 | |||
| LETMD1 | LETM1 domain containing 1 | |||
| FGFR3 | fibroblast growth factor receptor 3 | |||
| CPA4 | carboxypeptidase A4 | |||
| AURKA | aurora kinase A | |||
| CBS | cystathionine-beta-synthase | |||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | |||
| ADCY3 | adenylate cyclase 3 | |||
| TMEM79 | transmembrane protein 79 | |||
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | |||
| PTTG1 | pituitary tumor-transforming 1 | |||
| PCDH7 | protocadherin 7 | |||
| miR-937-5p | 1.787 | CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | |
| KIAA0101 | KIAA0101 | |||
| EMILIN2 | elastin microfibril interfacer 2 | |||
| miR-5194 | 1.694 | KLHL24 | kelch-like family member 24 | |
| FAP | fibroblast activation protein, alpha | |||
| LBH | limb bud and heart development | |||
| PIM1 | pim-1 oncogene | |||
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | |||
| LETMD1 | LETM1 domain containing 1 | |||
| FGFR3 | fibroblast growth factor receptor 3 | |||
| KIAA0101 | KIAA0101 | |||
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | |||
| ARTN | artemin | |||
| IGFBP6 | insulin-like growth factor binding protein 6 | |||
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | |||
| MALL | small integral membrane protein 5 | |||
| SCD | LSM14B, SCD6 homolog B (S. cerevisiae) | |||
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
In red up-regulated and in green down-regulated genes in BE63/3 cells treated with EVE (5 or 100 nM) compared to CTR.