Figure 3.

Glyteer treatment inhibited IL-4-induced Ccl17 and Ccl22 production in an aryl hydrocarbon receptor (Ahr)-independent manner in BMDCs. (a–d) Data are expressed as mean ± S.E.M.; n = 3 for each group; * p < 0.05. IL-4-stimulated BMDCs were treated with Glyteer in the absence or presence of CH223191 for 24 h. Glyteer and CH223191 were administered at the same timing. Expression of Ccl17 (a) and Ccl22 (c) in BMDCs was analyzed by qRT-PCR. Production of Ccl17 (b) and Ccl22 (d) in culture supernatant was measured by ELISA.