Table 2.

ncRNAs regulating apoptosis by BCL-2 family members’ modulation.

ncRNA	BCL-2 Family Target	Molecular Mechanism	Source
miR-15/16	BCL-2	Direct targeting	[44]
miR-204	BCL-2	Direct targeting	[46]
miR-197	NOXA; BMF	Direct targeting	[47]
miR-663	PUMA	Direct targeting	[48]
miR-17/92	BIM	Direct targeting	[49]
miR-29	BIM; HRK; BMF; PUMA; BAK; MCL-1	Direct targeting	[50,51,52,87]
miR-34	BCL-2	Direct targeting	[59,61,71]
miR-335	BCL-W	Direct targeting	[63,64,80]
miR-125b	BCL-2; BCL-W; MCL-1	Direct targeting	[66,76]
miR-125b	BCL-XL	Indirect targeting	[66]
miR-101	MCL-1	Direct targeting	[67]
miR-519d	MCL-1	Direct targeting	[70]
miR-221/222	PUMA	Direct targeting	[72]
miR-216a	BCL-2	Direct targeting	[78]
miR-206	BCL-W	Direct targeting	[79]
lnc_ASNR	BCL-2	Nuclear retention of AUF1	[75]
MALAT1	BCL-2	Competing endogenous RNA for miR-125b	[76]
HOTTIP	BCL-2	Competing endogenous RNA for miR-216a	[78]
HOTAIR	BCL-W	Competing endogenous RNA for miR-206	[79]
RP11-436H11.5	BCL-W	Competing endogenous RNA for miR-335	[80]
TUG1	BAX	Epigenetic silencing by EZH2 recruitment	[81]
PR-lncRNA-1	BAX	P53 recruitment to target genes promoters	[82]
PR-lncRNA-10	BCL2L1; PUMA; BAX	P53 recruitment to target genes promoters	[82]
PANDA	PUMA; NOXA	Inhibition of NF-YA-dependent transcription	[83]
circHIPK3	MCL-1	Competing endogenous RNA for miR-29	[87]
circUBAP2	BCL-2	Competing endogenous RNA for miR-143	[88]
circ-Foxo3	PUMA	Inhibition of MDM2-mediated FOXO3 degradation	[89]