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. 2018 Apr 6;19(4):1102. doi: 10.3390/ijms19041102

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Usefulness of SCCA2 as a biomarker for pediatric AD patients (modified from [25]). (A) Serum SCCA2 and thymus and activation-regulated chemokine (TARC) levels in control subjects and AD children and ROC curve analysis of SCCA2 (red solid line) and TARC in all AD children. (B) Association of Objective Scoring Atopic Dermatitis (O-SCORAD) with SCCA2 and TARC in the AD children. It is of note that the area under the curve (AUC) for SCCA2 is higher than that of TARC in panel A and that serum SCCA2 levels show better correlation with O-SCORAD than do serum TARC levels. *p < 0.01, ** p < 0.001.