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. 2018 Mar 27;19(4):1005. doi: 10.3390/ijms19041005

Figure 2.

Figure 2

Atypical meningioma (A–D). Immunostaining for CD68 (A), CD163 (B), iNOS (C), and HIF-1α (D). Note a CD68 positive signal in sheet-like growth areas (arrowheads) and in scattered macrophages (arrow). CD163 positivity is lower and immunoreactivity for HIF-1α is very low. Meningothelial meningioma (E–H). Immunostaining for CD68 (E), CD163 (F), iNOS (G), and HIF-1α (H). A more marked positivity for CD163 is evident. Note that CD68 positivity into the whorl is more marked than CD163 staining (Arrows) and strong positivity for HIF-1α.