Figure 3.

Representative images showing the activation of astrocytes and the microglia in the spinal cord after the Th9 compression and the atorvastatin treatment. Immunostaining of the astrocytes and microglial cells at the Th9 level of intact animals (A,D). Increased expression of the astrocytes (B) and the microglia (E) 24 h after the injury at the lesion site. The administration of ATR (5 mg/kg; i.p., immediately after the SCI) reduced the density of the activated astrocytes (C) and decreased the massive activation of the microglial cells (F). Scale bars: (A–F—100 µm; a–f—1000 µm). Atorvastatin—ATR; GFAP—astrocytes; Iba-1—microglia; SCI—spinal cord injury.