ADP	adenosine diphosphate
alt-NHEJ	alternative non-homologous end-joining
AOA1	ataxia with oculomotor apraxia 1
Arg	arginine
AsiDNA	a signal interfering DNA
ATM	ataxia telangiectasia mutated
ATR	ataxia telangiectasia and rad3-related
AUNIP	aurora kinase A and ninein interacting protein
BRCA1	breast cancer gene 1
BRCA2	breast cancer gene 2
CAKs	CDK activating kinases
Cas	CRISPR-associated nuclease
cdc25	cell division cycle 25
CDKs	cyclin-dependent kinases
CDKIs	CDK inhibitors
Chk1	checkpoint kinase 1
Chk2	checkpoint kinase 2
CRISPR	clustered regularly interspaced short palindromic repeats
CtIP	C-terminal-binding protein interacting protein
Dbait	DNA strand break bait
DDR	DNA damage response
DNA	deoxyribonucleic acid
DNA-PK	DNA-dependent protein kinase
DNA-PKCS	DNA-PK catalytic subunit
dsDNA	double-strand DNA
ERCC1	excision-repair cross-complementation group 1
Exo1	exonuclease 1
FDA	Food and Drug Administration
FEN1	flap endonuclease 1
G	glycine
G0	resting
G1	growth 1/gap 1
G2	pre-mitotic/gap 2
gRNA	guide RNA
H	histidine
H2O2	hydrogen peroxide
HR	homologous recombination
INK	CDK4 inhibitor
iPSCs	induced pluripotent stem cells
KIP	CDK inhibitor
LDL	low density lipoprotein
Lys	lysine
M	mitotic
mHtt	mutant huntingtin gene
MLH1	MutL homolog 1
MMEJ	microhomology-mediated end-joining
MRE11	dsDNA break repair nuclease MRE11
MRN	MRE11-RAD50-NBS1
MSH1	MutS homolog 1
MSH2	MutS homolog 2
MSH3	MutS homolog 3
MSH6	MutS homolog 6
mTOR	mammalian target of rapamycin
MutH	Mutator H
MutL	Mutator L
MutS	Mutator S
MutSα	MSH2-MSH6 heteroduplex
MutSβ	MSH2-MSH3 heteroduplex
Myt1	myelin transcription factor 1
N	asparagine
NAD+	nicotinamide adenine dinucleotide
NBS1	nibrin
NHEJ	non-homologous end-joining
O2	oxygen
O2−	superoxide
PAM	protospacer adjacent motif
PARP1	poly (ADP-ribose) polymerase 1
PAXX	paralog of XRCC4 and XLF
PCNA	proliferating cell nuclear antigen
PI3K	phosphatidylinositol 3 kinase
PIKKs	phosphoinositide 3 kinase-related kinases
RAD50	dsDNA break repair protein RAD50
RNA	ribonucleic acid
RNS	reactive nitrogen species
ROS	reactive oxygen species
RPA	replication protein A
S	DNA synthesis
SCAN1	spinocerebellar ataxia with axonal neuropathy
Ser	serine
SSA	single-strand annealing
SSAP	single-strand annealing protein
ssDNA	single-strand DNA
TFIIH	transcription factor II human
Tim	Timeless
Tipin	Tim-interacting protein
USP4	ubiquitin-specific protease 4
XLF	XRCC4-like factor
XPA	xeroderma pigmentosum group A
XPB	xeroderma pigmentosum group B
XPC-RAD23B	xeroderma pigmentosum group C-RAD23 homolog B
XPD	xeroderma pigmentosum group D
XPF	xeroderma pigmentosum group F
XPG	xeroderma pigmentosum group G
XRCC1	X-ray repair cross-complementation protein 1
XRCC4	X-ray repair cross-complementation protein 4
Zn	zinc