Figure 2.

Behavioral performance in the open field and object recognition. (A) Habituation to the open field. All mice habituated to the open field (effect of trial, p < 0.001), but there was no effect of irradiation. (B) Object recognition. Sham-irradiated mice and mice irradiated with 21 cGy or 168 cGy showed object recognition and spent more time exploring the novel object than the familiar object, but mice irradiated with 42 cGy showed impaired object recognition. Control: n = 13 mice; 21 cGy: n = 23 mice; 42 cGy: n = 20 mice; 168 cGy: n = 16 mice. * p < 0.05 versus familiar object; ** p < 0.01 versus familiar object.