| AD | Alzheimer’s disease |
| NFTs | Neurofibrillary tangles |
| CSF | cerebrospinal fluid |
| MMP | matrix-metalloproteinases |
| PHFs | paired helical filaments |
| APP | amyloid precursor protein |
| ACh | acetylcholine |
| TNAP | tissue-nonspecific alkaline phosphatase |
| PLP | pyridoxal 5′-phosphate |
| GABA | gamma-aminobutyric acid |
| CNS | central nervous system |
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