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. 2018 Mar 25;19(4):977. doi: 10.3390/ijms19040977

Figure 5.

Figure 5

Coupling percentage and Gj of co-expressing AF-linked mutants with wildtype Cx43. (A) Representative Ijs are shown from N2A cell pairs co-expressing Cx40, K107R, L223M, Q236H, or I257L (with an untagged reporter GFP) with wildtype Cx43 (with an untagged reporter DsRed); (B) bar graph illustrates coupling percentages of N2A cell pairs expressing each combination. The number of transfections is indicated; (C) bar graph illustrates the Gj of cell pairs co-expressing one of the Cx40 mutants (K107R, L223M, Q236H, or I257L) with Cx43. The Gj of cell pairs co-expressing Q236H:Cx43 was significantly lower than that of wildtype Cx40:Cx43 (* p < 0.05). The number of cell pairs is indicated.