K107R	Forward: 5′ CAGGAGAAGCGCAGGCTACGGGAGGCC 3′
	Reverse: 5′ GGCCTCCCGTAGCCTGCGCTTCTCCTG 3′
L223M	Forward: 5′ CTCCTCCTTAGCATGGCTGAACTCT 3′
	Reverse: 5′ AGAGTTCAGCCATGCTAAGGAGG 3′
I257L	Forward: 5′ CCCTCTGTGGGCCTAGTCCAGAGCTGC3′
	Reverse: 5′ GCAGCTCTGGACTAGGCCCACAGAGGG3′
Q236H	Forward: 5′ GGAAGAAGATCAGACACCGATTTGTCAAACC3′
	Reverse: 5′ GGTTTGACAAATCGGTGTCTGATCTTCTTCC3′