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. 2018 Apr 18;19(4):1223. doi: 10.3390/ijms19041223

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Representative immunostaining of runt-related transcription factor 2 (A,B), tartrate-resistant acid phosphatase (C,D) and van Gieson (E,F) in metastatic lesions with high (A,C,E) and low (B,D,F) bone cell activity. The area with newly formed bone is indicated with an arrow and magnified (E). Bar indicates 200 µm.

Representative immunostaining of runt-related transcription factor 2 (A,B), tartrate-resistant acid phosphatase (C,D) and van Gieson (E,F) in metastatic lesions with high (A,C,E) and low (B,D,F) bone cell activity. The area with newly formed bone is indicated with an arrow and magnified (E). Bar indicates 200 µm.