| ΔΔG | Gibb’s free energy |
| AAS | Amino acid substitution |
| BLAST | Basic Local Alignment Search Tool |
| CPR | Correct prediction ratio |
| DSC | Differential scanning calorimetry |
| FN | False negative |
| FP | False positive |
| GC2 | Generalized squared correlation |
| MCC | Matthews correlation coefficient |
| ML | Machine learning |
| MPRA | Massively parallel reporter assay |
| MSA | Multiple sequence alignment |
| NPV | Negative predictive value |
| PPV | Positive predictive value |
| QM | Quantum mechanics |
| TN | True negative |
| TNR | True negative rate |
| TP | True positive |
| TPR | True positive rate |