Figure 1.
Anti-oxidative property of Lycogen™ and potency comparison of lycopene and lycogen™. The structure of lycopene (a) and Lycogen™ (b) were showed. Lycogen™ structures, including ζ-carotene, neurosporene, spheroidenone, and methoxyneurosporene were illustrated. (c) Detection of ROS in lycogen™-treated HK-2 cell. Histogram showing the relative fluorescence intensity of H2DCFDA labelling cells. Significant reduction of ROS level was observed in 10 and 20 µM lycogen™-treated HK-2 cell. (d) Cell viability of DU145 cell with either lycopene or lycogen™ treatment were measured by MTT assay. Histogram showing the dose-dependent decrease of lycogen™ treated DU145 cell. Significant reduction of cell viability by 20 µM lycogen™ treatment was marked. Error bars represent ± SD. * p <0.05, ** p <0.01 and *** p <0.001, Student’s t-test.