Table 1.
Demographic and clinical test results.
| Parameters | Control | DED | p-Values |
|---|---|---|---|
| Age (years) | 50.7 ± 24.0 | 50.6 ± 19.6 | 0.98 |
| Sex, female/male (%) | 60/40 | 72/28 | |
| Symptoms (years) | 0 ± 0 | 5.0 ± 4.7 | <0.01 |
| OSDI score | 6.2 ± 4.4 | 67.8 ± 21.4 | <0.01 |
| Schirmer test (mm) | 24.7 ± 4.1 | 12.5 ± 8.8 | <0.02 |
| Break-up time (s) | 14.4 ± 2.3 | 5.4 ± 3.3 | <0.01 |
| Oxford score | 0 ± 0 | 1.4 ± 1.6 | <0.01 |
| Assessment of pain (/10) | 0 ± 0 | 6.1 ± 2.9 | <0.01 |
Fifteen control subjects and 32 patients with DED were enrolled in this clinical study. Data are expressed as mean ± standard deviation (SD). Statistical analyses between the two groups were performed using the nonparametric Mann-Whitney test. Level of statistical significance, p < 0.05. OSDI: Ocular Surface Disease Index.