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. 2018 Apr 6;19(4):1095. doi: 10.3390/ijms19041095

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparing top Gene Ontology (GO) Kyoto Encyclopedia of Genes and Genomes (KEGG) terms associated with high-fat diet (HFD)-responsive genes in brown adipose tissue (BAT). Enrichment analysis was performed using differentially expressed genes in BAT between HFD and low-fat diet (LFD) groups. (a) Heat-map showing top GO KEGG annotation terms in BAT between HFD and LFD groups. (b) GO KEGG terms associated with downregulated genes in BAT of HFD-fed obese mice. (c) GO KEGG terms associated with upregulated genes in BAT of HFD-fed obese mice.