Table 1.
Role of miRNAs in immunomodulation and cancer.
| microRNA | Tumor | Action | References |
|---|---|---|---|
| miR-21 | NSCLC; Neuroblastoma | Increase inflammation | [93,96] |
| miR-29a | NSCLC | Increase inflammation | [93] |
| miR-222-3p | Epithelial ovarian carcinoma | M2 TAM-like macrophages polarization | [94] |
| miR-223 | Breast Cancer | Invasiveness enhancement | [95] |
| miR-155 | Neuroblastoma; Dendritic cell |
Telomerase activity alteration and Cisplatin resistance; Increase inflammation |
[96,97,98] |
| miR-24-3p | Nasopharyngeal carcinoma | Anti-tumor immunity suppression | [4,99] |
| miR-891a | Nasopharyngeal carcinoma | Anti-tumor immunity suppression | [4,99] |
| miR-106a-5p | Nasopharyngeal carcinoma | Anti-tumor immunity suppression | [4,99] |
| miR-1908 | Nasopharyngeal carcinoma | Anti-tumor immunity suppression | [4,99] |
| miR-20a-5p | Nasopharyngeal carcinoma | Anti-tumor immunity suppression | [4,99] |
| miR-214 | Sarcoma | Anti-tumor immunity suppression | [100] |
| miR-212-3p | Pancreatic cancer | Immuno tolerance induction | [101] |
| miR-203 | Pancreatic adenocarcinoma | Anti-tumor immunity suppression | [89] |
| miR-146a | Dendritic cell | Reduce inflammation | [97,98] |
| miR-210 | Lung cancer; myelogenous leukemia cell lines | Immune escaping | [102,103] |
| miR-23a | Lung cancer; myelogenous leukemia | Immune escaping | [102] |
| miR-4498 | Melanoma | Anti-tumor immunity suppression | [104] |