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. 2018 Apr 9;19(4):1120. doi: 10.3390/ijms19041120
UDCA ursodeoxycholate
GUDCA glycine ursodeoxycholate
TUDCA taurousodeoxycholate
EE 17α-ethinylestradiol
Mrp2/MRP2 multidrug resistance-associated protein 2
MTX methotrexate
GSH reduced gluthathione
Nrf2 nuclear factor-E2-released factor 2
Ntcp Na+-taurocholate co-transporting polypeptide
Oat organic anion transporter
Oatp organic anion transporting polypeptide
Bsep bile salt export pump
ALT alanine aminotransferase
AST aspartate aminotransferase
PG propylene glycol
CMC carboxymethyl cellulose
BUN blood urea nitrogen
PBS phosphate buffered saline
LC-MS/MS liquid chromatography tandem-mass spectrometry
RT-PCR real-time reverse-transcription polymerase chain reaction
Hprt hypoxanthine phosphoribosyltransferase
IS internal standard
SDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresis
β-NAD β-nicotinamide adenine dinucleotide
3α-HSD 3α-hydroxysteroid dehydrogenase
EDTA ethylenediaminetetraacetic acid
AUC area under the plasma concentration–time curve
CLtotal total clearance
CLurine urinary clearance
CLbile biliary clearance
GFR glomerular filtration rate
CLcr creatinine clearance
CLGF glomerular filtration clearance
CLup,liver liver uptake clearance
CLup,kidney kidney uptake clearance
CLexc,bile biliary excretion clearance
CLexc,urine urinary excretion clearance