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. 2018 Apr 16;19(4):1208. doi: 10.3390/ijms19041208

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The Hippo signalling pathway identified as the most regulated by detected differentially expressed miRNAs depends on muscle mass. Green frame represents genes engaged in the pathway. Targeted genes regulated by identified miRNAs were marked orange (genes included in more than one pathway) and yellow (genes included only in one pathway) (KEGG database; hsa04390). Black arrows stand for a molecular interaction or relation, while dotted arrows stand for an indirect link or unknown reaction.