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. 2018 Apr 16;19(4):1203. doi: 10.3390/ijms19041203
VEGF vascular endothelial growth factor
PlGF placental growth factor
Rho Ras homologue gene
Rap Ras-related protein
ERK extracellular signal-regulated kinase
PI3 phosphoinositide-3
PIP3 phosphatidylinositol (3,4,5)-trisphosphate
eNOS endothelial nitric oxide synthase
MAP mitogen-activated protein
ROS reactive oxygen species
ROCK Rho kinase
MLC myosin light chain
NRP neuropilin
GEF guanine nucleotide exchange factor
FGF fibroblast growth factor
S1P sphingosine 1-phosphate
HUVEC human umbilical vein endothelial cell
CCM cerebral cavernous malformation