Figure 1.
Plaque formation in aortic arch of ApoE KO mice. (a) Representative images of aortic arch stained with oil red-O solution and (b) plaque area in aortic arch of ApoE KO mice exposed to CS. Quantitative data are expressed relative to the values of the control group. Data are mean ± SEM of six animals per group; (c) Cumulative acetylcholine-induced relaxation in aortic rings from ApoE KO mice exposed to CS. Data are mean ± SEM of four-six animals per group. * p < 0.05 versus the high-dose group.