Table 4.
Swelling degree of C-Dex, TSPO-Dex conjugates and TSPO-Dex NGs after 2 h.
| Tablet | Swelling PBS pH 7.4 | ||||
|---|---|---|---|---|---|
| Polymer | Nanogels | Polymer | Nanogels | ||
| t, min | (w/w, %) | t, min | (w/w, %) | ||
| TSPO-Dex 7 | TSPO-Dex NGs 7 | 120 | 18.1 ± 2.0 | 45 | 22.6 ± 2.5 |
| TSPO-Dex 8 | TSPO-Dex NGs 8 | 120 | 15.2 ± 2.4 | 45 | 19.0 ± 1.9 |
| TSPO-Dex 10 | TSPO-Dex NGs 10 | 90 | 6.5 ± 2.1 | 60 | 7.8 ± 0.7 |
| TSPO-Dex 11 | TSPO-Dex NGs 11 | 90 | 9.2 ± 3.0 | 60 | 11.1 ± 1.0 |
| C-Dex 6 | - | 20 | 31.5 ± 4.6 | - | - |
| C-Dex 9 | - | 20 | 27.4 ± 2.5 | - | - |
Measurements in the swelling study were performed in triplicate (means ± SD are shown). The values reported were taken at equilibrium (when three consecutive determinations gave the same weight).