Table 4.

List of active substances derived from Streptomyces spp. (in bold) and registered as commercial products in different geographical areas (data collected and modified into a table from [193,203,204,205]).

Biocontrol Metabolite (Bold) and Commercial Names	Organism	Country	Targeted Pathogen/Disease
Blasticidin-S BLA-S	S. griseochromogenes	USA	Rice blast (Pyricularia oryzae)
Kasugamycin Kasumin, Kasurab	S. kasugaensis	Ukraine	Leaf spot in sugar beet and celery (Cercospora spp.) and scab in pears and apples (Venturia spp.), soybean root rot (Phytophthora sojae)
Streptomycin Agrimycin, Paushak, Cuprimicin 17, AAstrepto 17, AS-50, Dustret, Cuprimic 100 and 500	S. griseus	India, USA, New Zealand, China, Ukraine, Canada	Bacterial rots, canker, and other bacterial diseases, Xanthomonas oryzae, Xanthomonas citri, and Pseudomonas tabaci of pome fruit, stone fruit, citrus, olives, vegetables, potatoes, tobacco, cotton, and ornamentals
Phytomycin Mycoshield, Cuprimic 100 and 500, Mycoject	S. rimosus	-	Fire blight (Erwinia amylovora) and diseases caused by Pseudomonas and Xanthomonas sp. and mycoplasma-like organisms
Validamycin Validacin, Valimun, Dantotsupadanvalida, Mycin Hustler, Valida, Sheathmar	S. hygroscopicus	-	Rhizoctonia solani and other Rhizoctonia in rice, potatoes, vegetables, strawberries, tobacco, ginger, cotton, rice, sugar beet, etc.
Polyoxorim Endorse, PolyoxinZ, Stopit, Polyoxin AL and Z, Polybelin	S. cacaoi var. asoensis	-	Plant pathogenic fungi, Sphaerotheca spp. and other powdery mildews, Botrytis cinerea, Sclerotinia sclerotiorum, Corynespora melonis, Cochliobolus miyabeanus, Alternaria alternate and other species in vines, apples, pears, vegetables, and ornamentals. Rice sheath blight (R. solani), apple, pear canker, and Helminthosporium in rice; also inhibits cell wall biosynthesis and causes abnormal germ tube swelling of spores and hyphal tips, rendering fungus nonpathogenic
Natamycin Delvolan	S. natalensis and S. chattanoogensis	-	Basal rots on daffodils and ornamentals caused by Fusarium oxysporum
Abamectin (Avermectins) Agri-Meck Avid, Clinch, Dynamec, Vertimec, Abacide, Abamex, Vapcomic, Vibamec, Agromec, Belpromec, Vamectin 1.8 EC, Vivid and many others	S. avermitilis	European Union, Worldwide	Mites, leaf miners, suckers, beetles, fire ants, and other insects in ornamentals, cotton, citrus, pome and nut fruit, vegetables
Polynactin Mitecidin	S. aureus	Japan	Spider mites (Tetranychus cinnabarinus), two-spotted mite (Tetranychus urticae), European red mite (Panonychus ulmi) in orchard fruit trees
Milbemycine Milbeknock, Koromite, Mesa, Ultiflora and Matsuguard	S. hygroscopicus subsp. aureolacrimosus	-	Citrus red mites, Kanzawa spider mites, and leaf miners in citrus, tea, eggplant