Table 2.

In silico alteration of nucleotides to generate alternative SNP alleles, resulting in putative gain or loss of transcription factor binding sites.

SNPs	Variation	Predicted Transcription Factor Binding Site
		Gain a	Loss b	Transcription Factor Binding Sequence c	Score
SNP1	−304A>C	-	Sp1	CCCCC	100
SNP2	−285G>A	AP-2	-	CCCAGGG	100
SNP3	−209A>C	-	MyoD	CAGCC	100
SNP4	−203A>G	CP1	-	ATTGC	100
SNP5	−188T>C	-	SRF	TTCCTC	100

Note: ^a,b Generated after substitution of allele 1 (wild type) with allele 2 (mutant); ^c Based on TFSEARCH analysis.