Figure 8.

MCF‐7 tumor cell growth inhibition mediated by NLG919/IR780 micelles. A) Administration route of NLG919/IR780‐micelle‐mediated PTT and immunotherapy. B) Tumor volume of primary tumor and secondary tumor versus time, respectively (n = 5). The knockdown of thymus in balb/C‐nu mice leads to depletion of T cells, which limits the immunotherapeutic outcome mediated by NLG919/IR780 micelles in the secondary tumor. It also demonstrates that the activation of T cells is the main mechanism underlying NLG919/IR780‐micelle‐mediated PTT/immunotherapy.